This research was supported by the Innovative Research Groups of the Natural Science Foundation of Hubei Province (2019CFA015), the National Natural Science Foundation of China (No. 31772615) and the projects of Wuhan Science and Technology Bureau (2018020401011304).
机构署名：
本校为第一且通讯机构
院系归属：
动物科学与营养工程学院
摘要：
This study was aimed to investigate whether eicosapentaenoic acid (EPA) and arachidonic acid (ARA), the representative n-3 or n-6 polyunsaturated fatty acids (PUFA), could alleviate enterotoxigenic Escherichia coli (ETEC) K88-induced inflammation and injury of intestinal porcine epithelial cells 1 (IPEC-1) by modulating pyroptosis and necroptosis signaling pathways. IPEC-1 cells were cultured with or without EPA or ARA in the presence or absence of ETEC K88. EPA and ARA reduced ETEC K88 adhesion and endotoxin content in the supernatant. EPA and...
