期刊论文

Analysis of Antimicrobial Susceptibility and Surveillance of Virulence Genes in Salmonella Isolates from Ningbo China

Shi, Xianming(xmshi@sjtu.edu.cn)

中文

中国食品学报

1009-7848

2019

19

2

216-222

10.16429/j.1009-7848.2019.02.027

国家“十三五”重点研发计划项目(2017YFC1600100) 国家自然科学基金青年科学基金项目(31601562).

本校为其他机构

目前宁波地区沙门氏菌对常用抗生素的耐受情况及主要毒力基因携带率的系统检测尚未见报道。本研究选取2006—2013年间宁波地区分离获得的121株沙门氏菌(共27个血清型),对其进行耐药谱检测,相关耐药基因及毒力基因筛查。结果显示:对12种常见抗生素的耐药率依次是:氨苄西林19.8%,四环素13.2%,强力霉素12.4%,复方新诺明11.6%,氯霉素8.7%,链霉素6.6%,妥布霉素3.3%,头孢曲松2.5%,环丙沙星0.8%,诺氟沙星0%,庆大霉素0%,阿米卡星0%。耐药基因携带率:bla_(TEM) 100%,bla_(PSE) 29.2%,bla_(CMY-2) 4.2%,bla_(CTX) 8.3%, bla_(SHV) 0%,tetA 100%,tetB 100%,tetG 70.8%,tetC 20.8%,sulI 100%,sulII 100%,sul...

121 Salmonella isolates (27 serotypes) obtained from 2006 to 2013 from Ningbo were examined for antimicrobial susceptibility and positive rates of major virulence genes. Among these 121 Salmonellae isolates, 19.8% were resistant to ampicillin, followed by tetracycline (13.2%), doxycycline (12.4%), trimethoprim / Sulfamethoxazole (11.6%), chloramphenicol (8.7%), streptomycin (6.6%), tobramycin (3.3%), ceftriaxone (2.5%), ciprofloxacin (0.8%), norfloxacin (0%), gentamicin (0%) and amikacin (0%). Among 24 strains with resistance to β-lactam antibiotic, the positive rate of the virulence gene...