期刊论文

Liang Jing-Yu

英文

中国天然药物

2095-6975

2012

10

5

370-373

10.1016/S1875-5364(12)60074-0

This was supported by the HMBC (Fig. 1) correlations of H-1ƍ with C-1ƍƍ and H-1ƍƍ with C-1ƍ. The configuration of C-1ƍ was determined as S ([Į]D 31.0 í30.1) by comparison of the optical rotation with 1ƍS-acetoxychavicol acetate ([Į]D25 ˉ60.1) [9]. Thus, compound 1 was elucidated as (S)-1'-ethoxy chavicol acetate.

本校为第一机构

AIM: To study the chemical constituents and bioactivity of the rhizomes of Alpinia galangal Willd. (Zingiberaceae). METHODS: The chemical constituents were isolated using various chromatographic methods and crystallization, and the chemical structures were elucidated on the basis of spectral analysis. In addition, cytotoxic activities toward four tumor cell lines (HepG2, EC109, A549 and Vero) were tested by MTT method. RESULTS: Six phenylpropanoids were obtained and their structures were identified as (S)-1’-ethoxy chavicol acetate (1), (E)-4-...

目的：研究大高良姜的化学成分及活性。方法：运用各种柱色谱方法和重结晶手段分离纯化化合物, 并通过波谱数据鉴定化合物结构。此外, 运用 MTT 法测定了化合物对四种肿瘤细胞株（HepG2, EC109, A549 和 Vero）的细胞毒活性。结果：从大高良姜中分离得到 6 个苯丙素类化合物, 其结构分别鉴定为（S）-1＇-ethoxy chavicol acetate （1）, （E）-4-acetoxy cinnamyl ethylether （2）, （E）-4-hydroxy-cinnamaldehyde （3）, （E）-4-acetoxy cinnamyl alcohol （4）, 4-acetoxy cinnamyl acetate （5） 和 4, 4＇[（2E, 2＇E）-bis（prop-2-ene）-1, 1＇-oxy]-diphenyl-7, 7＇-diacetate （6）....