期刊论文

Liang Jing-Yu

英文

中国天然药物

2095-6975

2014

12

2

139-141

10.1016/S1875-5364(14)60022-4

[Received on] 20-Dec.-2012 [Research funding] This project was supported by the Fundamental Research Funds for the Central Universities, China (No. JKY2011015). [ Corresponding author] LIANG Jing-Yu˖Prof., Tel: 86-25-83271 415, E-mail: jyliang08@126.com These authors have no conflict of interest to declare. Copyright © 2014, China Pharmaceutical University. Published by Elsevier B.V. All rights reserved

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Aim: To study the chemical constituents of the rhizomes of Alpinia officinarum Hance. Method: Compounds were isolated by repeated column chromatography, and their structures were elucidated on the basis of spectral analysis. The cytotoxic activities of these compounds were evaluated with the T98G and B16F10 cell lines by the MTT assay. Results: A dimeric diarylheptanoid, named alpinin B (1), along with three known diarylheptanoids were obtained, and their structures were identified as alpinin B (1), 1, 7-diphenyl-3,5-heptanedione (2), (4E)-1, 7...

试图学习 Alpinia officinarum Hance 的根茎的化学成分。方法混合物被重复的列层析孤立，并且他们的结构被阐明根据光谱分析。这些混合物的细胞毒素的活动被 MTT 试金与 T98G 和 B16F10 房间行评估。结果 A 二聚的 diarylheptanoid ，命名 alpinin B ( 1 )，与三已知的 diarylheptanoids 一起被获得，并且他们的结构作为 alpinin B ( 1 )被识别， 1 ， 7-diphenyl-3,5-heptanedione ( 2 )，( 4E )-1, 7-diphenylhept-4-en-3-one ( 3 )并且( 4E )-7-( 4-hydroxyphenyl ) -1-phenylhept-4-en-3-one ( 4 )。结论化合物 1 是新二聚的 diarylheptanoid。1 的 biosynthetic 小径被推测从在混合物之间...