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Effect of Radix Isatidis on the expression of moesin mRNA induced by LPS in the tissues of mice

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成果类型:
期刊论文
作者:
Li Jing*;Liu Yunhai;Fang Jianguo;Chen Xin;Xie Wei
通讯作者:
Li Jing
作者机构:
[Liu Yunhai; Fang Jianguo; Li Jing; Xie Wei] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Peoples R China.
[Chen Xin] Wuhan Polytech Univ, Dept Biotechnol & Pharm Engn, Wuhan 430023, Peoples R China.
通讯机构:
[Li Jing] H
Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Peoples R China.
语种:
英文
关键词:
Radix Isatidis;lipopolysaccharide (LPS);membrane-organizing extension spike protein mRNA (moesin mRNA)
关键词(中文):
板蓝根;脂多糖刺激;小鼠组织;膜突蛋白;mRNA表达
期刊:
当代医学科学
ISSN:
2096-5230
年:
2007
卷:
27
期:
2
页码:
135-137
基金类别:
This project was supported by grants from National Natural Sciences Foundation (No. 39870872 and No. 39170877) and a grant from the Ministry of Health of China (No. 98-2-110).
机构署名:
本校为其他机构
院系归属:
生命科学与技术学院
摘要:
To investigate the effect of the anti-endotoxic part of Radix Isatidis on the expression of moesin mRNA in murine tissues induced by lipopolysaccharide (LPS), the sample solution of F022 part from Radix Isatidis was intraperitoneally administered to experimental mice, and the lipopoly-saccharide (LPS) were injected into the tail vein, and then the tissues of liver, kidney and spleen were colleted and cut into slices. The mRNA was detected by moesin mRNA hybridization in situ. The staining results were observed under microscope. It was found tha...

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