Multipartite nonlocality, a measure of multipartite quantum correlations, is used to characterize topological quantum phase transitions (QPTs) in an infinite-size spin-1/2 two-leg Kitaev ladder model. First of all, the nonlocality measure
$${\mathcal {S}}$$
is singular at the critical points, thus these topological QPTs are accompanied by dramatic changes of multipartite quantum correlations. The influence of the inter-chain coupling upon multipartite nonlocality is also investigated. Furthermore, we carry out scaling analysis and find that the logarithm measure scales linearly as
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