Recently, diagnosis, therapy and monitoring of human diseases involve a variety of imaging modalities, such as magnetic resonance imaging (MRI), computed tomography (CT), Ultrasound (US) and Positron-emission tomography (PET) as well as a variety of modern optical techniques. The degeneration of lumbar intervertebral disc has become a common disease in modern society. Currently, the most commonly used method is the diagnostic grade based on MRI technology, among which Pfinmann grading system is most widely used in clinic. The Pfinmann grading system is mainly based on the measurement of the av...