会议论文

The interference effect of oxidized fish oil in the darkbarbel catfish lipid metabolism mediated by PPARα and SREBP1, and subsequent recovery

中文

2015

466-466

第十届世界华人鱼虾营养学术研讨会

第十届世界华人鱼虾营养学术研讨会论文集

2015-10-22

武汉

中国水产学会

本校为第一机构

　　采用60d的生长实验研究氧化鱼油对瓦氏黄颡鱼(Pelteobaggrus vachelli)脂肪代谢的干扰作用,并探讨PPARα 和SREBP1是否介导其干扰作用,随后通过60d恢复实验研究其恢复效果.共配制4种等氮等脂实验饲料,其中对照组不添加氧化鱼油,其他3个处理组氧化鱼油添加量分别为4(LOO),6(MOO),8％(HOO),分别补充8、4、2、0％的新鲜鱼油至8％的总外源脂肪添加量.实验结果表明,在氧化鱼油饲喂阶段：各氧化鱼油组的终末体重(FBW)和特定生长率(SGR)均显著低于对照组(P＜0.05).MOO组和HOO组血浆中胆固醇(TC)及肝脏中甘油三酯(TG)含量均显著低于对照组(P＜0.05).各氧化鱼油组肝中PPARα mRNA表达量均显著低于对照...

　　A 60-day feeding trial was conducted to investigate the interference effects of oxidized fish oil in the darkbarbei catfish lipid metabolism,and to identify whether this interference effect was mediated by PPARa and SREBP1,and then subsequent recovery was used to test the recovery capability when the fish were then switched back to the control diet for a further 60d.Four diets of graded oxidized oil levels of 4(control),6(LOO),8(MOO)and 9%(HOO)were evaluated at same dietary lipid level(8 g/100g diet).During the oxidized oil feeding period,t...