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Multi-omics profiling reveals Poria cocos polysaccharides mitigate PEDV-induced intestinal injury by modulating lipid metabolism in piglets

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成果类型:
期刊论文
作者:
Zhang, Qian;Wang, Shuaijie;Wu, Mengjun;Tan, Zihan;Wu, Tao;...
通讯作者:
Hou, YQ
作者机构:
[Wang, Shuaijie; Wu, Tao; Hou, Yongqing; Zhang, Qian; Wu, Mengjun; Wang, Lei; Tan, Zihan; Zhao, Di; Yi, Dan] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
通讯机构:
[Hou, YQ ] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
Intestinal injury;Lipid metabolism;Piglets;Porcine epidemic diarrhea virus;Poria cocos polysaccharides
期刊:
畜牧与生物技术杂志(英文)
ISSN:
1674-9782
年:
2025
卷:
16
期:
1
页码:
1-14
基金类别:
This work was jointly supported by the National Natural Science Foundation of China (32172763, U22A20514), the National Key R&D Program of China (2022YFD130040302), the Hubei Provincial Key R&D Program (2023BBB040), and the Hubei Important Science and Technology Project (2024BBA004).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
BACKGROUND: Porcine epidemic diarrhea virus (PEDV) infection poses a significant challenge to the swine industry, with limited effective control measures available. Poria cocos polysaccharides (PCP) is the primary active ingredient of Poria cocos, and has been demonstrated to show beneficial effects on intestinal damage in previous studies. However, its mechanism has not been fully understood. In the present study, 18 seven-day-old piglets were divided into 3 groups: Control group, PEDV group, and PCP + PEDV group. After three days of adaptat...

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