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Effect of l-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge:

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成果类型:
期刊论文
作者:
Zhu, H. L.;Liu, Y. L.*;Xie, X. L.;Huang, J. J.;Hou, Y. Q.
通讯作者:
Liu, Y. L.
作者机构:
[Zhu, H. L.; Liu, Y. L.; Hou, Y. Q.; Xie, X. L.; Huang, J. J.] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
通讯机构:
[Liu, Y. L.] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.
语种:
英文
关键词:
Lipopolysaccharide;arginine;intestinal mucosal immune barrier function;weaned pigs
期刊:
INNATE IMMUNITY
ISSN:
1753-4259
年:
2013
卷:
19
期:
3
页码:
242-252
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31172222, 30972109]; Program for New Century Excellent Talents in UniversityProgram for New Century Excellent Talents in University (NCET) [NCET-10-0158]; Key Project of Chinese Ministry of EducationMinistry of Education, China [209082]; Project of Natural Science Foundation of Hubei Province [2010CDA050, 2009CDB006]; Project of International Cooperation of Hubei Province [2011BFA008]; Hubei Provincial Department of Education [Q20111702]; Wuhan Science and Technology Program [201171034320]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
The effects of l-arginine (Arg) supplementation on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge were evaluated. Twenty-four weaned pigs were allotted to four treatments including: (i) non-challenged control; (ii) LPS-challenged control; (iii) LPS + 0.5% Arg; and (iv) LPS + 1.0% Arg. On d 16, pigs in the LPS, LPS + 0.5% Arg and LPS + 1.0% Arg groups were challenged by injection with 100 μg/kg of body mass LPS, whereas the control group were given sterile saline. At 48 h post-challenge, all pigs ...

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