Metabolic profiles in the response to supplementation with composite antimicrobial peptides in piglets challenged with deoxynivalenol

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成果类型：

期刊论文

作者：

Xiao, H.;Wu, M. M.;Shao, F. Y.;Tan, B. E.*;Li, T. J.;...

通讯作者：

Tan, B. E.

作者机构：

[Wu, M. M.; Xiao, H.; Tan, B. E.; He, Q. H.; Li, T. J.; Yin, Y. L.; Yin, J.; Wang, J.; Ren, W. K.; Shao, F. Y.] Chinese Acad Sci, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg,Minist Agr,Obse, Changsha 410125, Hunan, Peoples R China.

[Wu, M. M.; Yin, J.; Wang, J.; Ren, W. K.; Shao, F. Y.] Univ Chinese Acad Sci Beijing, Beijing 100080, Peoples R China.

[Tan, B. E.] Hunan Collaborat Innovat Ctr Utilizat Bot Funct I, Changsha 410000, Hunan, Peoples R China.

[Hou, Y. Q.] Wuhan Polytech Univ, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.

通讯机构：

[Tan, B. E.] C

Chinese Acad Sci, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg,Minist Agr,Obse, Changsha 410125, Hunan, Peoples R China.

语种：

英文

关键词：

Composite antimicrobial peptide;Deoxynivalenol;Liquid chromatography tandem mass spectrometry;Metabolic profiles;Piglets;Proton nuclear magnetic resonance spectroscopy

期刊：

Journal of Animal Science

ISSN：

1525-3163

年：

2015

卷：

期：

页码：

1114-1123

DOI：

10.2527/jas.2014-8229

基金类别：

973 National Projects SubjectNational Basic Research Program of China [2013CB127302, 2013CB127306]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31330075, 31372326]; Chinese Academy of Sciences Visiting Professorships for Senior International Scientists [2013T2S0012]; Guangzhou GLAM Biotechnology Co., Ltd

机构署名：

本校为其他机构

院系归属：

动物科学与营养工程学院

摘要：

Deoxynivalenol (DON) causes various toxic effects in human and animals. However, our previous studies have shown that composite antimicrobial peptides (CAP) can have a protective effect in piglets challenged with DON. This study was conducted to evaluate the effect of the CAP GLAM 180# on the metabolism of piglets challenged with DON using a nuclear magnetic resonance (NMR)-based metabolomics approach. A total of 28 individually housed piglets (Duroc × Landrace × Large Yorkshire) weaned at 28 d of age were randomly assigned into 4 treatment g...

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Metabolic profiles in the response to supplementation with composite antimicrobial peptides in piglets challenged with deoxynivalenol

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