National Natural Science Foundation of China [81671263, 81370031]; Major projects of Education Department of Anhui Province, China [KJ2021ZD0094]; Anhui Provincial Natural Science Foundation [2208085MH221]
机构署名：
本校为第一机构
摘要：
How to use bioinformatics methods to quickly and accurately locate the effective targets of traditional Chinese medicine monomer (TCM) is still an urgent problem needing to be solved. Here, we used high-throughput sequencing to identify the genes that were up-regulated after cells were treated with TCM monomers and used bioinformatics methods to analyze which transcription factors activated these genes. Then, the binding proteins of these transcription factors were analyzed and cross-analyzed with the docking proteins predicted by small molecule reverse docking software to quickly and accurate...
