期刊论文

Lu, Qirong;Qiu, YS

英文

Toxicon

0041-0101

2024

237

107531

10.1016/j.toxicon.2023.107531

This work was supported by National College Students Innovation and Entrepreneurship Training Program (grant number 202210496009). CRediT authorship contribution statement Defeng Wen: Methodology, Validation, Formal analysis, Investigation. Wantong Han: Methodology, Validation, Writing - original draft, Visualization. Quan Chen: Methodology, Formal analysis, Resources, Data curation, Project administration, acquisition. Guanhui Qi: Resources, Data curation, Project administration. Mengling Gao: Resources, Data curation, Project administration. Pu Guo: Conceptualization, Methodology, Writing - original draft. Yu Liu: Conceptualization, Methodology.

本校为第一且通讯机构

Contamination with fumonisin B1 (FB1) represents a global health problem. FB1 exposure may also trigger intestinal injury by activating inflammatory responses, leading to a reduction in production performance and economic benefits. However, the mechanism of FB1-induced intestinal inflammatory injury is still unclear. At the same time, it is urgent to develop antibiotic alternatives and therapeutic targets to alleviate antibiotic resistance and to ensure effective treatment of intestinal inflammatory injury. We combined network pharmacology and in vitro experiments to explore the core therapeut...