The Effect of Baicalin on the Expression Profiles of Long Non-Coding RNAs and mRNAs in Porcine Aortic Vascular Endothelial Cells Infected with Haemophilus parasuis

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成果类型：

期刊论文

作者：

Guo, Ling;Liu, Jun;Zhang, Yunfei;Fu, Shulin;Qiu, Yinsheng*;...

通讯作者：

Qiu, Yinsheng

作者机构：

[Zhang, Yunfei; Hu, Chien-An Andy; Liu, Yu; Hou, Yongqing; Ye, Chun; Qiu, Yinsheng; Wu, Zhongyuan; Liu, Jun; Fu, Shulin; Guo, Ling] Wuhan Polytech Univ, Sch Anim Sci & Nutr Engn, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

[Zhang, Yunfei; Liu, Yu; Hou, Yongqing; Ye, Chun; Qiu, Yinsheng; Wu, Zhongyuan; Liu, Jun; Fu, Shulin; Guo, Ling] Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan, Peoples R China.

[Hu, Chien-An Andy] Univ New Mexico, Sch Med, Biochem & Mol Biol, Albuquerque, NM 87131 USA.

通讯机构：

[Qiu, Yinsheng] W

Wuhan Polytech Univ, Sch Anim Sci & Nutr Engn, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

Haemophilus parasuis;baicalin;infection;lncRNAs;porcine aortic vascular endothelial cells;vascular injury

期刊：

DNA AND CELL BIOLOGY

ISSN：

1044-5498

年：

2020

卷：

期：

页码：

801-815

DOI：

10.1089/dna.2019.5340

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31572572, 31601922]

机构署名：

本校为第一且通讯机构

院系归属：

动物科学与营养工程学院

摘要：

Haemophilus parasuis can elicit serious inflammatory responses, which contribute to huge economic losses to the swine industry. However, the pathogenic mechanisms underlying inflammation-related damage induced by H. parasuis remain unclear. Accumulating evidence indicates that long non-coding RNAs (lncRNAs) have important functions in the regulation of autoimmune disorders. Baicalin has been shown to have anti-inflammatory, anti-microbial, and anti-oxidant activities. In this study, we investigated whether lncRNAs were involved in the vascular injury or inflammation triggered by H. parasuis an...

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The Effect of Baicalin on the Expression Profiles of Long Non-Coding RNAs and mRNAs in Porcine Aortic Vascular Endothelial Cells Infected with Haemophilus parasuis

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