期刊论文

Liu, Yulan

英文

INNATE IMMUNITY

1753-4259

2021

27

1

23-30

10.1177/1753425920971032

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Project of Innovative Research Groups of the Natural Science Foundation of Hubei Province (2019CFA015), the National Natural Science Foundation of Hubei Province (2018CFB527), the Open Project of Hubei Key Laboratory of Animal Nutrition and Feed Science (Grant 201804), and the National Natural Science Foundation of China (31702203).

本校为第一且通讯机构

To test the dynamic changes of the expression of genes and microRNA in the gastrocnemius muscle after LPS challenge, 36 piglets were assigned to a control group (slaughtered 0 h after saline injection) and LPS groups (slaughtered at 1 h, 2 h, 4 h, 8 h, and 12 h after LPS treatment, respectively). After LPS treatment, the mRNA expression of IL-1β, IL-6, and TNF-α reached maximal levels at 1 h, 2 h, and 1 h, respectively ( P < 0.05), and mRNA expression of TLR4, NODs, muscle-specific ring finger 1, and muscle atrophy F-box peaked at 12 ...