With the increasing aging population, there is a growing concern regarding the impact of skeletal muscle decay on the quality of life of the elderly. In this study, the anti-sarcopenia effect of the whey protein isolate-epigallocatechin gallate (WPI-EGCG) complex and its underlying mechanisms were investigated using a D-galactose induced senescence C2C12 cell model and skeletal muscle sarcopenia mouse model. The results showed that the optimal preparation conditions of the complex were pH 5.5, reaction time 1.5 h, and WPI:EGCG = 1:2.5. Under this condition, the DPPH free radical scavenging rat...