Dietary l-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs

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成果类型：

期刊论文

作者：

Han, J.;Liu, Y. L.*;Fan, W.;Chao, J.;Hou, Y. Q.;...

通讯作者：

Liu, Y. L.

作者机构：

[Liu, Y. L.; Hou, Y. Q.; Zhu, H. L.; Fan, W.; Han, J.; Chao, J.; Che, Z. Q.; Yin, Y. L.; Meng, G. Q.] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Wuhan 430023, Hubei, Peoples R China.

[Liu, Y. L.] China Agr Univ, State Key Lab Anim Nutr, Beijing 100094, Peoples R China.

[Liu, Y. L.] Chinese Acad Sci, Inst Subtrop Agr, Changsha 410125, Hunan, Peoples R China.

[Liu, Y. L.] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Changqing Garden, Wuhan 430023, Hubei, Peoples R China.

通讯机构：

[Liu, Y. L.] W

Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Changqing Garden, Wuhan 430023, Hubei, Peoples R China.

语种：

英文

关键词：

Arginine;Cyclophosphamide;Immunosuppression;Weaned pigs

期刊：

Amino Acids

ISSN：

0939-4451

年：

2009

卷：

期：

页码：

643-651

DOI：

10.1007/s00726-008-0184-9

基金类别：

This work was supported by the National Natural Science Foundation of China (30500362), the National Basic Research Program of China (2004CB117504), the Hubei Provincial Department of Education (D200718003), and the State Key Laboratory of Animal Nutrition (2007KLAN002).

机构署名：

本校为第一且通讯机构

院系归属：

动物科学与营养工程学院

摘要：

A study was conducted to investigate the effects of l-arginine (Arg) on performance and immune function in cyclophosphamide (CY) immunosuppressed weaned pigs. The weaned pigs were allotted randomly into one of three treatments, including: (1) non-challenged control; (2) CY-challenged group; and (3) CY + 0.5% Arg. On days 14 and 21 of the trial, pigs were injected with CY or sterile saline. Blood samples were obtained on days 21 and 28 of the trial for further analysis. On day 28, delayed-type hypersensitivity reaction was evaluated. Arg allevia...

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Dietary l-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs

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