期刊论文

Liu, Yulan

英文

INNATE IMMUNITY

1753-4259

2012

18

6

804-814

10.1177/1753425912441955

Program for New Century Excellent Talents in UniversityProgram for New Century Excellent Talents in University (NCET) [NCET-10-0158]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31172222, 30972109]; Chinese Ministry of EducationMinistry of Education, China [209082]; Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province [2010CDA050, 2009CDB006]; Wuhan Science and Technology Program [201171034320]

本校为第一且通讯机构

This study was conducted to evaluate whether dietary supplementation with L-arginine (Arg) could attenuate Escherichia coli LPS-induced liver injury through the TLR4 signaling pathway in weaned pigs. Eighteen weaned pigs were allotted to three treatments: non-challenged control, LPS challenged control and LPS-+-0.5% Arg. On d 18, pigs were injected with LPS at 100-μg/kg of body weight (BW) or sterile saline. Blood samples were obtained at 4-h post-injection. Pigs were then sacrificed for the collection of liver samples. Arg supplementation (0....