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MicroRNA in Skeletal Muscle: Its Crucial Roles in Signal Proteins, Mus cle Fiber Type, and Muscle Protein Synthesis

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成果类型:
期刊论文
作者:
Zhang, Jing;Liu, Yu Lan*
通讯作者:
Liu, Yu Lan
作者机构:
[Zhang, Jing; Liu, Yu Lan] Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.
通讯机构:
[Liu, Yu Lan] W
Wuhan Polytech Univ, Hubei Key Lab Anim Nutr & Feed Sci, Hubei Collaborat Innovat Ctr Anim Nutr & Feed Saf, Wuhan 430023, Peoples R China.
语种:
英文
关键词:
MicroRNAs;muscle fiber type;muscle protein synthesis;myogenesis;signal proteins;SNP
期刊:
CURRENT PROTEIN & PEPTIDE SCIENCE
ISSN:
1389-2037
年:
2017
卷:
18
期:
6
页码:
579-588
基金类别:
National Nature Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31422053]; Natural Science Foundation of Hubei Province, ChinaNatural Science Foundation of Hubei Province [2015CFB514]; Project of the Hubei Provincial Department of Education [T201508]
机构署名:
本校为第一且通讯机构
院系归属:
动物科学与营养工程学院
摘要:
Pork is one of the most economical sources of animal protein for human consumption. Meat quality is an important economic trait for the swine industry, which is primarily determined by prenatal muscle development and postnatal growth. Identification of the molecular mechanisms underlying skeletal muscle development is a key priority. MicroRNAs (miRNAs) are a class of small noncoding RNAs that have emerged as key regulators of skeletal muscle development. A number of muscle-related miRNAs have been identified by functional gain and loss experiments in mouse model. However, determining miRNA-mRN...

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