This work was funded by the National Key R&D Program of China (Grant No.2017YFC1600103); partially by a grant of National Natural Science Foundation of China (31471660).
机构署名:
本校为第一且通讯机构
院系归属:
生命科学与技术学院
摘要:
Citric acid and EGCG at their minimum inhibitory concentrations were tested in this study. Logarithmic phase cells of Escherichia coli O157:H7 (ATCC 43895) were exposed to EGCG and citric acid respectively. The results of RT-real time PCR showed that both EGCG and citric acid increased stx2 and oxyR expression and decreased stx1, recA and Q expression. The result of Western blotting for RecA protein further indicated that both EGCG and citric acid decreased RecA production. Both EGCG and citric acid increased the level of intracellular reactive...