Dynamic regulation of gut microbiota in high-fat or normal-fed mice by dietary phosphatidylcholine and phosphatidylethanolamine

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成果类型：

期刊论文

作者：

Shi, Zihui;Wang, Boya;Wang, Siqi;Tan, Hui;He, Junbo;...

通讯作者：

Lin, H

作者机构：

[Lin, Hong; Wang, Boya; Wang, Siqi; He, Junbo; Zhang, Weinong; Tan, Hui; Shi, Zihui] Wuhan Polytech Univ, Sch Food Sci & Engn, Wuhan, Peoples R China.

[Lin, Hong; He, Junbo; Zhang, Weinong] Wuhan Polytech Univ, Hubei Key Lab Proc & Transformat Agr Prod, Wuhan, Peoples R China.

[Lin, Hong; He, Junbo; Zhang, Weinong] Wuhan Polytech Univ, MOE Key Lab Deep Proc Major Grain & Oil, Wuhan, Peoples R China.

通讯机构：

[Lin, H ] W

Wuhan Polytech Univ, Sch Food Sci & Engn, Wuhan, Peoples R China.

语种：

英文

关键词：

Phosphatidylethanolamine;Phosphatidylcholine;Intestinal flora;High-fat diet

期刊：

Food Bioscience

ISSN：

2212-4292

年：

2025

卷：

页码：

107314

DOI：

10.1016/j.fbio.2025.107314

基金类别：

CRediT authorship contribution statement Zihui Shi: Writing – original draft, Investigation, Data curation. Boya Wang: Writing – original draft, Investigation, Data curation. Siqi Wang: Investigation. Hui Tan: Investigation. Junbo He: Data curation, Conceptualization. Weinong Zhang: Supervision, Conceptualization. Hong Lin: Writing – review & editing, acquisition, Conceptualization.

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

摘要：

Dietary phosphatidylcholine (PC) and phosphatidylethanolamine (PE) can remodel the intestinal flora. The aim of this study was to explore the dynamic alteration of gut microbiota induced by dietary PE and PC, using a 12-week high-fat diet mice model with soy-derived PE and egg yolk-derived PC intervention. Fecal microbiomes were analyzed at weeks 0, 1, 4, 8, 10, and 12 using 16S rRNA sequencing technique, and colonic bile acid composition was quantified by UPLC-MS/MS. Results showed that gut microbial structure stabilized at first eight weeks. ...

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Dynamic regulation of gut microbiota in high-fat or normal-fed mice by dietary phosphatidylcholine and phosphatidylethanolamine

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