期刊论文

Yi, D

英文

FRONTIERS IN IMMUNOLOGY

1664-3224

2024

15

1323866

10.3389/fimmu.2024.1323866

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was funded by National Natural Science Foundation of China (32072762, 32172763), National Key R&D Program of China (2022YFD130040207), the Foundation for Innovative Research Groups of Hubei Provincial Natural Science Foundation (2023AFA018), and the Hubei Provincial Department of Education (T2022024).

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The present study was conducted to decipher the protection effects of ellagic acid (EA) on piglets infected with porcine epidemic diarrhea virus (PEDV). Thirty 7-day-old piglets were randomly assigned to three treatment groups: control, PEDV, and EA + PEDV groups. After a 3-day period of adaption, piglets in the EA + PEDV group were orally administered with 20 mg/kg·BW EA during days 4-11 of the trial. On day 8, piglets were orally administered with PEDV at a dose of 10(6) TCID(50) (50% tissue culture infectious dose) per pig. Additionally, in...