Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolated from South-central in China

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yu, Xiao-li;Wen, Zi-lu;Chen, Gao-zhan;Li, Rui;Ding, Bing-bing;...

通讯作者：

Zhang, Shu-lin

作者机构：

[Li, Rui; Ding, Bing-bing; Wen, Zi-lu; Yu, Xiao-li; Chen, Gao-zhan] Wuhan Polytech Univ, Sch Biol & Pharmaceut Engn, Wuhan, Peoples R China.

[Zhang, Shu-lin; Yao, Yu-feng; Guo, Xiao-kui; Wen, Zi-lu; Yu, Xiao-li] Shanghai Jiao Tong Univ, Sch Med, Dept Med Microbiol & Parasitol, Shanghai 20025, Peoples R China.

[Wang, Hong-hai; Li, Yao; Wu, Hai] Fudan Univ, Inst Genet, State Key Lab Genet Engn, Shanghai 200433, Peoples R China.

通讯机构：

[Zhang, Shu-lin] S

Shanghai Jiao Tong Univ, Sch Med, Dept Med Microbiol & Parasitol, Shanghai 20025, Peoples R China.

语种：

英文

关键词：

Beijing genotypes;M. tuberculosis;extensively drug resistance;multidrug-resistance;mutation

期刊：

JOURNAL OF ANTIBIOTICS

ISSN：

0021-8820

年：

2014

卷：

期：

页码：

291-297

DOI：

10.1038/ja.2013.133

基金类别：

China Mega-Projects of Science Research for the 12th Five Year Plan [2012ZX10003002-002, 2013ZX10003002-005]; Educational Commission of Hubei, China [D20121809]; Science and Technology Commission of Shanghai MunicipalityScience & Technology Commission of Shanghai Municipality (STCSM) [12441903300]; Graduate Innovation Foundation of Wuhan Polytechnic University [2010CX016]

机构署名：

本校为第一机构

院系归属：

生命科学与技术学院

摘要：

Rifampicin (RIF) and isoniazid (INH) Mycobacterium tuberculosis isolates were characterized from South-central China and transmission patterns within the Beijing genotype were detected in multidrug-resistant isolates. Six genetic regions, including rpoB for RIF, and katG, inhA, ahpC, mabA-inhA promoter and oxyR-ahpC intergenic region for INH were analyzed by DNA sequencing in 60 multidrug-resistant isolates, including 7 extensively drug-resistant isolates. The genomic deletion RD105 was characterized by genotyping. The results showed that 91.7%...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolated from South-central in China

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问