Crash and noise in operation, dynamical optimization model regarding timing cam mechanism in internal combustion engine was built. Based on tabu search algorithms and Matlab, optimization simulation has been done. Compared with original design, the simulation results showed that plentiful coefficient increased by 1.24%, dynamical maximum positive acceleration lowered by 0.87% in ascending and increased by 5.23% in descending, the maximum negative acceleration decreased by 5.93%. The change of acceleration became more stable a...