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Circ_0058063 promotes progression of thyroid cancer by sponging miR-330-3p/SDC4 axis

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成果类型:
期刊论文
作者:
Tang, Mingwei;Wang, Fengbo;Wang, Ke;Jiang, Yuan;Wang, Qiongfen
通讯作者:
Wang, Q.
作者机构:
[Tang, Mingwei] Chengdu Med Coll, Dept Endocrinol & Metab, Clin Med Coll, Affiliated Hosp 1, Chengdu, Peoples R China.
[Wang, Fengbo; Wang, Ke; Jiang, Yuan; Wang, Qiongfen] Chengdu Med Coll, Clin Med Coll, Dept Rehabil Med, Affiliated Hosp 1, 278 Middle Sect Baoguang Ave, Chengdu 610500, Sichuan, Peoples R China.
通讯机构:
Department of Rehabilitation Medicine, Clinical Medical College of Chengdu Medical College, First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Sichuan, Chengdu, China
语种:
英文
关键词:
cell, circ_0058063;miR-330-3p;SDC4;thyroid cancer
期刊:
Anti-Cancer Drugs
ISSN:
0959-4973
年:
2022
卷:
33
期:
7
页码:
642-651
机构署名:
本校为第一机构
摘要:
Circular RNA takes a crucial part in carcinogenesis. Circ_0058063 has been found to act as an oncogene in esophageal cancer and bladder cancer, but its role in thyroid cancer (TC) is still under investigation. Therefore, we carried out a study to understand its role in TC and its association with miR-330-3p. The circ_0058063 and miR-330-3p in TC tissues and cells were quantified by quantitative reverse transcription PCR, and cell counting kit-8 and scratch adhesion test were conducted for evaluation of cell proliferation and migration. In addition, a dual luciferase reporter assay and RNA immu...

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