期刊论文

The Protective Effect of Essential Oil Compound on Lipopolysaccharide Stimulating the Liver of Piglets

中文

中国畜牧杂志

0258-7033

2018

54

3

87-91

10.19556/j.0258-7033.2018-03-087

国家重点研发计划专项（2016YFD0501210） 国家自然科学基金项目（31572416） 湖北省技术创新专项（重大项目）（2016ABA121）

本校为第一机构

试验旨在研究复合植物精油(OCT)对脂多糖(LPS)刺激仔猪肝脏的保护作用.选取18头仔猪,随机分为对照组、LPS组和OCT+LPS组,每组6个重复.对照组与LPS组饲喂基础日粮,OCT+LPS组在基础日粮中添加50 mg/kg OCT.试验期21 d.于试验第21天,LPS组与OCT+LPS组仔猪腹腔注射LPS,对照组注射等量的生理盐水,3h后采血,6h后屠宰.结果表明:与对照组相比,LPS刺激提高了血浆谷丙转氨酶(ALT)、谷草转氨酶(AST)、碱性磷酸酶(ALP)、谷酰转肽酶(GGT)、肝脏诱导型一氧化氮合酶(i-NOS)的活力(P＜0.05),肝脏热休克蛋白70 (HSP70)基因的相对表达量显著提高(P＜0.05);仔猪肝脏表皮生长因子(EGF)、白细胞介素10 (IL-10)、胰岛素...

This study was conducted to determine whether the essential oil compound（OCT） could alleviate the liver injury of lipopolysaccharide（LPS）-challenged piglets. Eighteen crossbred healthy piglets were randomly assigned into the control, LPS, and OCT＋LPS groups. Six pigs in every group. Piglets in the control and LPS groups were fed with the basal diet, whereas the OCT＋LPS group fed the basal diet supplemented with 50 mg/kg OCT. The experiment lasted for 21 days. On day 21 of the trial, Piglets in the LPS and OCT＋LPS groups were intraperiton...