期刊论文

Wang, Haibo

英文

International Journal of Biological Macromolecules

0141-8130

2019

128

885-892

10.1016/j.ijbiomac.2019.01.211

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21706201, 21676208, 21376183]; Wuhan Morning Light Plan of Youth Science and Technology, China [2017050304010326]; Hubei Provincial Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [2018CFA030, 2017CFB507]; Innovation Team Program of Hubei Province, China [T201208]

本校为第一且通讯机构

Side chain modification of collagen provides an attractive way to enhance their structure and functions, which is highly desirable for the development of promising biomaterials. However, the impact of structural change of side chains on the intrinsic self-assembly property of collagen was always ignored. Here, a series of acrylic acid-grafted-collagen (AA-g-Col) with different grafting density were prepared to explore the impact of side chain structural variation on the self-assembly of collagen. The results showed that excessive grafting density would weaken or even disappear the self-assembl...