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Early life stage exposure to cadmium and zinc within hour affected GH/IGF axis, Nrf2 signaling and HPI axis in unexposed offspring of marine medaka Oryzias melastigma

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成果类型:
期刊论文
作者:
Zhuo, Mei-Qin;Chen, Xiao;Gao, Lu;Zhang, Hai-Ting;Zhu, Qing-Ling;...
通讯作者:
Zheng, Jia-Lang;Liu, YF
作者机构:
[Zhuo, Mei-Qin] Wuhan Polytech Univ, Sch Anim Sci & Nutr Engn, Wuhan 430023, Peoples R China.
[Gao, Lu; Zhang, Hai-Ting; Zhu, Qing-Ling; Chen, Xiao] Zhejiang Ocean Univ, Marine Sci & Technol Coll, Zhoushan 316000, Peoples R China.
[Zheng, Jia-Lang; Zheng, JL; Liu, Yifan] Zhejiang Ocean Univ, Natl Engn Res Ctr Marine Facil Aquaculture, Zhoushan 316000, Peoples R China.
通讯机构:
[Zheng, JL; Liu, YF ] Z
Zhejiang Ocean Univ, Natl Engn Res Ctr Marine Facil Aquaculture, Zhoushan 316000, Peoples R China.
语种:
英文
关键词:
Fish;Hormesis;Metals;Stress response;Transgenerational effect
期刊:
Aquatic Toxicology
ISSN:
0166-445X
年:
2023
卷:
261
页码:
106628
基金类别:
This work was supported by National Natural Science Foundation of China ( 42106147 ) and Bureau of Science and Technology of Zhoushan ( 2019C21013 ).
机构署名:
本校为第一机构
院系归属:
动物科学与营养工程学院
摘要:
Information on transgenerational effects of cadmium (Cd) and zinc (Zn) within hour of exposure is scarce. To the end, larvae of marine medaka Oryzias melastigma at 0 day-post-hatching (dph) were subjected to LC(50) for 96-h of Cd or Zn for 0.5 and 6h, and then transferred into clear water for 95 days until the generation of offspring larvae at 25 dph. Growth, antioxidant capacity and stress response in offspring larvae were examined. Exposure to Zn for 0.5h or Cd for 0.5h and 6h promoted growth performance and reduced total antioxidant capacity (TAC) and activities of superoxide dismutase (SOD...

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