Intervention of pumpkin seed oil on metabolic disease revealed by metabonomics and transcript profile

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhao, Xiu-Ju*（赵秀举）;Chen, Yu-Lian;Fu, Bing;Zhang, Wen;Liu, Zhiguo*;...

通讯作者：

Zhao, Xiu-Ju（赵秀举）;Liu, Zhiguo

作者机构：

[Zhao, Xiu-Ju; Liu, Zhiguo; Chen, Yu-Lian] Wuhan Polytech Univ, Collaborat Innovat Ctr Proc Agr Prod Hubei Prov, Sch Biol & Pharmaceut Engn, 68 South Xuefu Rd,Changqing Garden, Wuhan 430023, Peoples R China.

[Zhao, Xiu-Ju] Chinese Acad Agr Sci, Oil Crops Res Inst, Hubei Key Lab Lipid Chem & Nutr Oil, Wuhan 430062, Peoples R China.

[Fu, Bing] Changyuan Cuisine Vocat & Tech Coll, Changyuan 453400, Peoples R China.

[Zhang, Wen] Shaanxi Univ Sci & Technol, Sch Food & Biol Engn, Xian 710021, Peoples R China.

[Zhuo, Hexian] Xinxiang Inst Drug Control Food & Drug Adm Xinxia, 17 Jiankang Rd, Xinxiang 453000, Peoples R China.

通讯机构：

[Zhao, XJ; Liu, ZG] W

Wuhan Polytech Univ, Collaborat Innovat Ctr Proc Agr Prod Hubei Prov, Sch Biol & Pharmaceut Engn, 68 South Xuefu Rd,Changqing Garden, Wuhan 430023, Peoples R China.

语种：

英文

关键词：

pumpkin seed oil (PSO);metabolic disease (MD);metabonomics;transcript profile

期刊：

Journal of the Science of Food and Agriculture

ISSN：

0022-5142

年：

2017

卷：

期：

页码：

1158-1163

DOI：

10.1002/jsfa.7842

基金类别：

Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences [201506]; Wuhan Polytechnic University [2015 s8]

机构署名：

本校为第一且通讯机构

院系归属：

食品科学与工程学院

生命科学与技术学院

摘要：

BACKGROUND: Understanding the metabolic and transcription basis of pumpkin seed oil (PSO) intervention on metabolic disease (MD) is essential to daily nutrition and health. RESULTS: This study analyzed the liver metabolic variations of Wistar rats fed normal diet (CON), high-fat diet (HFD) and high-fat plus PSO diet (PSO) to establish the relationship between the liver metabolite composition/transcript profile and the effects of PSO on MD. By using proton nuclear magnetic resonance spectroscopy together with multivariate data analysis, it was f...

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Intervention of pumpkin seed oil on metabolic disease revealed by metabonomics and transcript profile

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