期刊：
Ecotoxicology and Environmental Safety,2022年238:113568 ISSN：0147-6513
通讯作者：
Kui Zhu
作者机构：
[Huang, Xiaoyong; Zhu, Kui; Shao, Bing; Zhao, Xiaole; Peng, Wenjing] China Agr Univ, Coll Vet Med, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China.;[Zhao, Xiaole] Wuhan Polytech Univ, Inst Food Sci & Engn, Wuhan 430023, Peoples R China.;[Huang, Xiaoyong; Zhang, Xin; Shao, Bing] Beijing Ctr Dis Prevent & Control, Beijing Key Lab Diagnost & Traceabil Technol Food, Beijing 100013, Peoples R China.;[Zhu, Kui] 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China.;[Shao, Bing] 16 Hepingli Middle St, Beijing 100013, Peoples R China.
通讯机构：
[Kui Zhu] C;College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing 100193, People’s Republic of China
通讯机构：
[Na Xu; Tongcun Zhang] I;Institute of Biology and Medicine, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China
期刊：
International Journal of Food Properties,2022年25(1):1203-1214 ISSN：1094-2912
通讯作者：
Shoulei Yan
作者机构：
[Li, Jie; Yan, Shoulei; Liu, Yanzhao; Wang, Jie] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Peoples R China.;[Li, Jie; Yan, Shoulei] Yangtze River Econ Belt Engn Res Ctr Green Dev Bu, Minist Educ, Wuhan, Peoples R China.;[Li, Jie; Yan, Shoulei] Hubei Aquat Vegetable Preservat Proc Engn Technol, Wuhan, Peoples R China.;[Diao, Ying] Wuhan Polytech Univ, Coll Life Sci & Technol, Wuhan, Peoples R China.;[Hu, Zhongli] Wuhan Univ, Coll Life Sci, Hubei Lotus Rhizome Engn Technol Res Ctr, Wuhan, Peoples R China.
通讯机构：
[Shoulei Yan] C;College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China<&wdkj&>Yangtze River Economic Belt Engineering Research Center for Green Development of Bulk Aquatic Bioproducts Industry of Ministry of Education, Wuhan, China<&wdkj&>Hubei Aquatic Vegetable Preservation Processing Engineering Technology Research Center, Wuhan, China
关键词：
Lotus rhizome starch;Adulteration;Ferrous sulfate;polyphenol;Liquid chromatography mass spectrometry;Colorimetric card
摘要：
Lotus rhizome starch (LRS) is an important traditional processed product of lotus rhizome in China due to its good taste and high nutritional value. However, adulterated lotus rhizome starches are prevalent on the market. In this study, a novel method for the rapid detection of adulteration in LRS based on color reaction between ferrous sulfate (FS) and (-)-gallocatechin (GC) in LRS was studied. The polyphenols in LRS were analyzed by liquid chromatography-mass spectrometry (LC-MS/MS) as GC and (+)-catechin, and GC could show a bluish color with FS solution. LRS showed a bluish color when FS solution (0.01 mol/L) was used as the chromogenic agent, which was not observed for other ten kinds of starches tested in this work. There was an obvious color gradient when FS solution was used to react with adulterated LRS at different proportions, and the change in blue color was obvious when maize starch or cassava starch was adulterated in LRS at the ratio of 6:4. Then, a semi-quantitative method was used to make a color card according to the color gradient, which was then successfully used to detect the adulteration of four kinds of commercial LRS. The results indicate that the proposed method may facilitate the simple, effective and efficient detection of adulteration in LRS.
通讯机构：
[Yulan Liu] H;Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan Polytechnic University, Wuhan 430023, China<&wdkj&>Author to whom correspondence should be addressed.
摘要：
Stressors cause activation of the hypothalamic-pituitary-adrenal (HPA) axis and a systemic inflammatory response. As a newly proposed cell death manner in recent years, necroptosis occurs in a variety of tissue damage and inflammation. However, the role of necroptosis in HPA axis activation remains to be elucidated. The aim of this study was to investigate the occurrence of necroptosis and its role in HPA activation in a porcine stress model induced by Escherichia coli lipopolysaccharide (LPS). Several typical stress behaviors like fever, anorexia, shivering and vomiting were observed in piglets after LPS injection. HPA axis was activated as shown by increased plasma cortisol concentration and mRNA expression of pituitary corticotropin-releasing hormone receptor 1 (CRHR1) and adrenal steroidogenic acute regulatory protein (StAR). The mRNA expression of tumor necrosis factor alpha (TNF-alpha), interleukin-1 beta (IL-1 beta) and IL-6 in the hypothalamus, pituitary gland and adrenal gland was elevated by LPS, accompanied by the activation of necroptosis indicated by higher mRNA expression of necroptosis signals including receptor-interacting protein kinase (RIP) 1, RIP3, and phosphorylated mixed-lineage kinase domain-like protein (MLKL). Furthermore, necrostatin-1 (Nec-1), an inhibitor of necroptosis, inhibited necroptosis indicated by decreased mRNA levels of RIP1, RIP3, MLKL, and phosphoglycerate mutase family member 5 (PGAM5) in the hypothalamus, pituitary gland and adrenal gland. Nec-1 also decreased the mRNA expression of TNF-alpha and IL-beta and inhibited the activation of the HPA axis indicated by lower plasma cortisol concentration and mRNA expression of adrenal type 2 melanocortin receptor (MC2R) and StAR. These findings suggest that necroptosis is present and contributes to HPA axis activation induced by LPS. These findings provide a potential possibility for necroptosis as an intervention target for alleviating HPA axis activation and stress responses.
通讯机构：
[Ding, Baoan] C;[Tang, Biao] S;College of Agriculture and Animal Husbandry, Qinghai University, Xining, 810016, China.;State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products & Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
通讯机构：
[Yunliang Zhao; Renbo Gao] H;Hubei Key Laboratory of Mineral Resources Processing and Environment, Wuhan University of Technology, 122 Luoshi Road, Wuhan, Hubei, 430070, China<&wdkj&>School of Resources and Environmental Engineering, Wuhan University of Technology, 122 Luoshi Road, Wuhan, Hubei, 430070, China
关键词：
Solar steam generation;MXene;Montmorillonite nanosheets;Gel;Water treatment
摘要：
Solar steam generation is an environment-friendly, low-cost, efficient and sustainable approach to produce fresh water, which has been widely researched recently as a promising technology. However, practical application of solar steam generation is always restricted by the photothermal conversion efficiency and long-term stability. Herein, the self-assembly hierarchical binary gel (HBG) containing a MXene (Ti3C2) gel as the upper structure and montmorillonite (MMT) gel as based materials was designed to achieve the efficient solar desalination toward water purification applications. The result indicated that Ti3C2 gel exhibited high light absorption efficiency (over 94%) in a wide solar spectrum range, meanwhile, MMT gel showed remarkable thermal isolation with a low conductivity of 0.04366 (W/m.K) as well as quick water supply ability. In addition, the HBG achieved the evaporation rate of 1.37 kg m(-2) h(-1) with the high photothermal conversion efficiency of 93.7%. This hierarchical design also performed an excellent stability in cycle tests and salt-rejecting experiments as well as achieved remarkable water purification performance by rejecting organics and metal ions. In a word, the HBG is proved to be an efficient and advanced design with excellent stability for solar steam generation.
通讯机构：
[Wang, S.] S;State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Food Nutrition and Safety, Ministry of Education of China, Tianjin University of Science and Technology, Tianjin, China
通讯机构：
[Gang Liu] P;[Wenjing Huang; Hao Zhao] C;College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, China<&wdkj&>CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, China<&wdkj&>Pharmacy Department, Renmin Hospital of Wuhan University, Wuhan, China
摘要：
By quenching the electronic excited state, self-aggregation of photosensitizers deteriorates the photodynamic therapy (PDT) outcome. Previously reported strategies to mitigate aggregation-caused-quenching (ACQ) involve harsh conditions and tedious synthesis processes. Moreover, failure to tune the extent of photosensitizer aggregation on-demand usually leads to a sub-optimal PDT effect. Herein, a new insight into ACQ alleviation by precisely tailoring the aggregation extent of photosensitizers via the confinement effect is unraveled by concise and facile coordination co-assembly fabrication of Pt/TCPP NCPs. Optimized meso-tetra(4-carboxyphenyl)porphine (TCPP) aggregation extent was achieved by precisely regulating the PES/TCPP feeding ratio to 12, unleashing outstanding PDT efficacy for robustly synergistic cancer PDT/chemotherapy.
期刊：
International Journal of Environmental Research and Public Health,2022年19(20):13114- ISSN：1661-7827
通讯作者：
Zeyu Wang
作者机构：
[Gao, Shiya] Wuhan Polytech Univ, Sch Management, Wuhan 430023, Peoples R China.;[Dong, Xiufang; Wang, Zeyu] Guangzhou Univ, Sch Publ Adm, Guangzhou 510006, Peoples R China.;[Jiang, Shaoxiang] Peking Univ, Natl Sch Dev, Beijing 100871, Peoples R China.;[Ding, Wen] Univ Waterloo, Fac Engn, Waterloo, ON N2L 6J5, Canada.;[Wang, Yuchen] Johns Hopkins Univ, Carey Sch Business, Baltimore, MD 21202 USA.
通讯机构：
[Zeyu Wang] T;These authors contributed equally to this work.<&wdkj&>School of Public Administration, Guangzhou University, Guangzhou 510006, China<&wdkj&>Author to whom correspondence should be addressed.
关键词：
FCEM manufacturing enterprises;enterprise digital transformation;health and safety management;internet of things;big data technology;FCEM
摘要：
As far as we know, for large manufacturing enterprises, there is often a community of labor gathered around such enterprises, which is especially used as a place for the enterprise to place the labor force. This paper aimed to update the industry model of Chinese Manufacturing Enterprises (CMEs) to improve workers’ health management. This work first discusses the value, mode, and process of Enterprise Digital Transformation (EDT) and Worker Health and Safety Management (WHSM). Then, it proposes the CMEs-oriented EDT model and WHSM system based on Big Data Technology (BDT) and the Internet of Things (IoT). The proposed model and system are verified through a case study on the Shanghai BYD manufacturing enterprise (short for BYD) using the Fuzzy Comprehensive Evaluation Method (CFEM). The EDT model verification considers the adaptation and performance of enterprises after EDT. The WHSM system considers workers’ oxygen inhalation status to evaluate their heart and cardiovascular health. The results show that EDT improves the enterprise’s revenue and reshuffles the revenue structure. The EDT model has absolute adaptability to BYD. It has greatly improved BYD’s indexes, especially financial performance, market capability, and technical capability.
作者机构：
[Xiong, Juan; Hu, Jin-Feng; Osman, Ezzat E. A.; Yang, Guoxun; Wu, Xiying] Fudan Univ, Sch Pharm, Dept Nat Med, Shanghai 201203, Peoples R China.;[Wan, Jiang; Hu, Jin-Feng; Wu, Xiying] Taizhou Univ, Sch Pharmaceut Sci, Inst Nat Med & Hlth Prod, Zhejiang Prov Key Lab Plant Ecol & Conservat, Taizhou 318000, Peoples R China.;[Zhu, Quangang; Wu, Xiying] Tongji Univ, Shanghai Skin Dis Hosp, Sch Med, Shanghai 200443, Peoples R China.;[Tang, Yu] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Peoples R China.;[Osman, Ezzat E. A.] Theodor Bilharz Res Inst, Dept Med Chem, Kornaish El Nile St, Giza 12411, Egypt.
通讯机构：
[Jin-Feng Hu; Yu Tang; Quangang Zhu] A;Authors to whom correspondence should be addressed.<&wdkj&>These authors contributed equally to this work.<&wdkj&>College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China<&wdkj&>Authors to whom correspondence should be addressed.<&wdkj&>Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China<&wdkj&>Authors to whom correspondence should be addressed.<&wdkj&>Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai 201203, China<&wdkj&>Institute of Natural Medicine and Health Products, School of Pharmaceutical Sciences, Zhejiang Provincial Key Laboratory of Plant Ecology and Conservation, Taizhou University, Taizhou 318000, China
关键词：
Platanus x acerifolia;Platanaceae;flavonoid glycosides;antibacterial;Staphylococcus aureus
摘要：
Despite the rapid advances in drug R&D, there is still a huge need for antibacterial medications, specifically for the methicillin-resistant Staphylococcus aureus (MRSA). Inspired by the research where a viable class of MRSA inhibitors was found in the species Platanus occidentalis, a S. aureus inhibition screening-guided phytochemical reinvestigation on Platanus x acerifolia (London plane tree) leaves were performed with four flavonoid glycosides garnered, including two new compounds, quercetin-3-O-alpha-l-(2 ''-E-p-coumaroyl-3 ''-Z-p-coumaroyl)-rhamnopyranoside (E,Z-3 '-hydroxyplatanoside, 1) and quercetin-3-O-alpha-l-(2 ''-Z-p-coumaroyl-3 ''-E-p-coumaroyl)-rhamnopyranoside (Z,E-3 '-hydroxyplatanoside, 2). All of the isolates showed significant S. aureus ATCC 25904 inhibitory activity with MICs ranging from 4 to 64 mu g/mL, suggesting the potential of discovering drug leads for the control of S. aureus from such a rich, urban landscaping plant in the Platanus genus.
